- Advanced Fertility Procedures
IUI & ICSI: Understanding Your Options
Not every fertility journey needs IVF. IUI and ICSI are two advanced, effective procedures that address different causes of infertility — often as a simpler first step, or as a precise solution for male factor infertility.
- The Basics
What Are IUI & ICSI?
IUI (Intrauterine Insemination) places specially prepared sperm directly into the uterus around the time of ovulation, increasing the chances of fertilisation without a laboratory-based procedure.
ICSI (Intracytoplasmic Sperm Injection) is a specialised IVF technique where a single healthy sperm is injected directly into an egg — used specifically for male factor infertility where sperm quality or count is a concern.
IUI vs. ICSI — What's the Difference?
IUI
A simpler, less invasive procedure often tried before IVF.
- Best for mild male factor infertility or unexplained infertility
- No anaesthesia or laboratory fertilisation required
- Performed during a natural or mildly stimulated cycle
- Lower cost than IVF or ICSI
ICSI
A precise laboratory technique performed as part of an IVF cycle.
- Best for significant male factor infertility (low count, poor motility)
- A single sperm is injected directly into each retrieved egg
- Performed alongside full IVF stimulation and egg retrieval
- Higher fertilisation rates in male factor cases
- IUI or ICSI?
Who Should Consider IUI or ICSI?
- Personalised Care
IUI is recommended for
Mild male factor infertility, cervical mucus issues, unexplained infertility, or couples using donor sperm.
- Personalised care
ICSI is recommended for
Significant male factor infertility, previous failed fertilisation with standard IVF, or when using frozen or surgically retrieved sperm.
- Personalised care
Both require
A basic fertility evaluation for both partners to confirm which approach best fits your specific situation.
Common Questions
Is IUI painful?
No. IUI is a quick, in-office procedure similar to a Pap smear — most patients describe mild discomfort at most, and it requires no anaesthesia.
How many IUI cycles are typically tried before moving to IVF?
Most specialists recommend 3–4 IUI cycles before considering IVF, though this depends on your age and specific diagnosis. Dr. Harshlata will guide this decision based on your individual response.
Does ICSI guarantee fertilisation?
ICSI significantly improves fertilisation rates for male factor infertility, but like all fertility treatments, it cannot guarantee a specific outcome. Success depends on egg quality and other individual factors.
Is ICSI more expensive than standard IVF?
ICSI adds a modest additional cost to a standard IVF cycle, since it involves an extra laboratory step. Dr. Harshlata will provide a transparent cost breakdown during your consultation.
Find the Right Path for You
Every case is different. Book a consultation to understand whether IUI, ICSI, or another approach best fits your situation.